Platelet-derived growth factor analyzers SEB-C100
Khoom taw qhia
Platelet Derived Growth Factor Analyzer yog qhov ntsuas thiab ntsuas ntsuas raws li tus qauv ntsuas tshwj xeeb uas tau tsim los ntawm peb lub tuam txhab.Tus kws tshuaj ntsuam xyuas pom cov txiaj ntsig ntawm platelet-derived kev loj hlob, ib qho tshwj xeeb cov cim protein nyob rau hauv tib neeg cov zis uas tsim thaum cov hlab ntsha coronary stenosis tshwm sim.Kev tsom xam tuaj yeem ua tiav hauv ob peb feeb los ntawm kev siv 1 ml ntawm cov zis xwb.Tus kws tshuaj ntsuam xyuas tuaj yeem txiav txim siab seb cov hlab ntsha coronary puas muaj stenosis thiab qib ntawm stenosis thiaj li muab kev siv rau kev kuaj ntxiv.Kev tshawb nrhiav thiab kev soj ntsuam txoj kev ntawm platelet-derived growth factor analyzer yog ib qho tseem ceeb uas tsis yog-invasive nrhiav kom tau txoj kev, uas tsis tas yuav tsum tau txhaj tshuaj thiab auxiliary tshuaj, tshem tawm cov teeb meem uas tib neeg tsis haum rau iodine-muaj contrast agents tsis muaj peev xwm mus rau CT thiab lwm yam coronary. artery angiography.Lub ntsuas ntsuas muaj qhov zoo ntawm cov nqi ntsuas qis, ntau yam ntawm daim ntawv thov, daim ntawv thov yooj yim, kev ntsuas ceev ceev, thiab lwm yam, thiab yog hom tshiab ntawm cov hlab ntsha stenosis thaum ntxov thiab kuaj ntsuas ntsuas.
Analyzer muaj qhov zoo hauv qab no:
1. Ceev ceev: Muab cov zis tso rau hauv lub tshuab kuaj pom thiab tos ob peb feeb xwb
2. Kev yooj yim: Kev ntsuam xyuas tsis yog muaj nyob hauv tsev kho mob nkaus xwb.Lawv tuaj yeem ua tau ntawm cov chaw kuaj mob, tsev laus lossis cov tsev laus hauv zej zog
3. Kev nplij siab: Tsuas yog 1ml ntawm cov zis tsuas yog xav tau raws li cov qauv, tsis muaj ntshav rub, tsis muaj tshuaj, tsis muaj qhov sib txawv, tsis muaj kev txhawj xeeb txog kev tsis haum tshuaj
4. Kev txawj ntse: Kev soj ntsuam zoo tag nrho, ua haujlwm tsis muaj neeg saib xyuas
5. Ib qho yooj yim einstallation: me me, tuaj yeem ntsia tau thiab siv nrog ib nrab lub rooj
6. Kev saib xyuas yooj yim: Tsis siv neeg saib xyuas thiab qhia cov khoom siv tau yooj yim hloov pauv tau yooj yim
Txoj cai ntawm cov khoom
Raman spectroscopy siv lub teeb tawg kom nrawm nrawm rau cov qauv molecular.Cov txheej txheem no yog raws li lub hauv paus ntsiab lus uas thaum lub teeb irradiates ib molecule, elastic collisions tshwm sim thiab ib feem ntawm lub teeb tawg.Qhov zaus ntawm lub teeb tawg yog qhov sib txawv ntawm qhov sib txawv ntawm qhov teeb meem tshwm sim, hu ua Raman tawg.Qhov kev siv ntawm Raman scattering associates nrog lub molecule tus qauv, tso cai rau kev soj ntsuam ntawm nws cov kev siv thiab zaus los txiav txim lub molecule qhov xwm thiab qauv precisely.
Vim tsis muaj zog Raman teeb liab thiab nquag fluorescence cuam tshuam, tau txais Raman spectra thaum lub sij hawm kuaj pom tseeb tuaj yeem nyuaj.Kev tshawb pom zoo ntawm Raman teeb liab yog qhov nyuaj tiag tiag.Yog li ntawd, qhov chaw kho kom zoo nkauj Raman spectroscopy tuaj yeem txhim kho qhov kev siv ntawm Raman tawg tawg lub teeb, hais txog cov teeb meem no.Cov txheej txheem cov ntsiab lus tseem ceeb yog muab cov khoom siv los kuaj pom ntawm cov hlau tshwj xeeb, xws li nyiaj lossis kub.thiaj li tsim tau ib tug ntxhib, nanometer-theem nto, ua rau ib tug nto-txhim kho nyhuv.
Nws tau pom tias Raman spectrum ntawm cov cim platelet-derived kev loj hlob zoo (PDGF-BB) muaj qhov sib txawv ntawm qhov siab ntawm 1509 cm-1.Tsis tas li ntawd, nws tau tsim kom muaj qhov muaj cov cim platelet-derived growth factor (PDGF-BB) hauv cov zis cuam tshuam nrog cov hlab ntsha stenosis.
Los ntawm Kev Siv Raman spectroscopy thiab cov cuab yeej txhim kho saum npoo, PDGF analyzer tuaj yeem ntsuas qhov muaj PDGF-BB thiab nws cov yam ntxwv peaks 'kev siv cov zis.Qhov no ua rau kev txiav txim siab seb cov hlab ntsha coronary yog stenotic thiab qib ntawm stenosis, yog li muab lub hauv paus rau kev kuaj mob.
Keeb kwm ntawm cov khoom
Nyob rau hauv xyoo tas los no, feem ntau ntawm cov kab mob plawv tau maj mam nce ntxiv vim kev hloov pauv ntawm kev noj haus thiab kev ua neej nyob, nrog rau cov neeg laus.Qhov kev tuag ntawm tus kab mob coronary plawv tseem ceeb heev.Raws li Tuam Tshoj Kev Noj Qab Haus Huv Kev Noj Qab Haus Huv thiab Kab Mob Tshaj Tawm 2022, kev tuag ntawm cov kab mob plawv ntawm cov neeg nyob hauv Suav nroog yuav yog 126.91/100,000 thiab 135.88/100,000 ntawm cov neeg nyob deb nroog hauv 2020. Daim duab tau nce ntxiv txij li 201. nyob rau hauv cov cheeb tsam nyob deb nroog.Hauv xyoo 2016, nws tau dhau ntawm theem hauv nroog thiab txuas ntxiv mus rau xyoo 2020. Tam sim no, coronary arteriography yog thawj txoj kev kuaj mob uas siv hauv chaw kho mob txhawm rau kuaj mob plawv.Thaum hu ua "tus qauv kub" rau kev kuaj mob plawv, nws qhov kev tawm tsam thiab tus nqi siab tau coj mus rau kev txhim kho ntawm electrocardiography raws li kev hloov pauv hloov lwm txoj kev kuaj mob.Txawm hais tias kev kuaj mob electrocardiogram (ECG) yog qhov yooj yim, yooj yim, thiab pheej yig, kev kuaj mob tsis raug thiab kev tsis pom zoo ntawm kev kuaj mob tseem tuaj yeem tshwm sim, ua rau nws tsis muaj kev ntseeg siab rau kev kuaj mob ntawm cov kab mob plawv.Yog li ntawd, txoj kev loj hlob ntawm ib txoj kev uas tsis yog-invasive, siab rhiab heev, thiab txhim khu kev qha txoj kev rau thaum ntxov thiab sai nrhiav tau ntawm cov kab mob plawv yog qhov tseem ceeb heev.
Surface-enhanced Raman spectroscopy (SERS) tau pom ntau daim ntawv thov hauv kev tshawb fawb txog lub neej rau kev kuaj xyuas biomolecules ntawm qhov tsis tshua muaj siab.Piv txwv li, Alula et al.Nws muaj peev xwm txheeb xyuas cov feeb ntawm creatinine hauv cov zis los ntawm kev siv SERS spectroscopy nrog cov duab catalytically hloov cov nyiaj nanoparticles uas muaj cov khoom sib nqus.
Ib yam li ntawd, Ma et al.ua hauj lwm magnetically induced aggregation ntawm nanoparticles nyob rau hauv SERS spectroscopy los qhia tsis tshua muaj concentrations ntawm deoxyribonucleic acid (DNA) nyob rau hauv cov kab mob.
Platelet-derived growth factor-BB (PDGF-BB) ua lub luag haujlwm tseem ceeb hauv kev txhim kho atherosclerosis los ntawm ntau lub tshuab thiab muaj kev sib raug zoo rau cov kab mob plawv.Enzyme-linked immunosorbent assay (ELISA) yog txoj hauv kev tseem ceeb siv hauv kev tshawb fawb PDGF-BB tam sim no txhawm rau kuaj pom cov protein no hauv cov hlab ntsha.Piv txwv li, Yuran Zeng thiab cov npoj yaig tau txiav txim siab plasma concentration ntawm PDGF-BB los ntawm kev siv enzyme-linked immunosorbent assay thiab pom tau tias PDGF-BB pab txhawb kev loj hlob ntawm cov kab mob carotid atherosclerosis.Hauv peb txoj kev tshawb fawb, peb thawj zaug txheeb xyuas SERS spectra ntawm ntau yam PDGF-BB aqueous cov kev daws teeb meem uas tsis tshua muaj siab, siv peb 785 nm Raman spectroscopy platform.Peb pom tias cov yam ntxwv ncov nrog Raman hloov ntawm 1509 cm-1 tau muab tso rau hauv cov kua dej ntawm PDGF-BB.Tsis tas li ntawd, peb pom tias cov yam ntxwv ncov no tseem cuam tshuam nrog cov kua dej ntawm PDGF-BB.
Peb lub tuam txhab tau koom tes nrog pab pawg tshawb fawb hauv tsev kawm los ua SERS spectroscopy tsom xam ntawm tag nrho ntawm 78 cov qauv zis.Cov no suav nrog 20 tus qauv los ntawm cov neeg mob uas tau phais PCI, 40 cov qauv los ntawm cov neeg mob uas tsis tau txais kev phais PCI, thiab 18 cov qauv los ntawm cov neeg noj qab haus huv.Peb ua tib zoo txheeb xyuas cov zis SERS spectra los ntawm kev sib koom ua ke ntawm Raman peaks nrog Raman zaus hloov ntawm 1509cm-1, uas yog txuas ncaj qha rau PDGF-BB.Kev tshawb fawb tau qhia tias cov zis kuaj ntawm cov neeg mob uas tau txais kev phais PCI tau pom tus yam ntxwv siab kawg ntawm 1509cm-1, thaum lub ncov no tsis nyob hauv cov zis kuaj ntawm cov neeg noj qab haus huv thiab feem ntau cov neeg mob uas tsis yog PCI.Nyob rau tib lub sijhawm, thaum lub tsev kho mob cov ntaub ntawv kho mob ntawm coronary angiography tau muab tso ua ke, nws tau txiav txim siab tias txoj kev kuaj pom no ua tau zoo nrog kev txiav txim siab seb puas muaj cov kab mob plawv ntau dua 70%.Tsis tas li ntawd, txoj kev no tuaj yeem kuaj pom qhov rhiab heev thiab qhov tshwj xeeb ntawm 85% thiab 87% feem, qhov ntsuas ntawm qhov txhaws ntau dua 70% ntawm cov kab mob plawv los ntawm kev txheeb xyuas cov yam ntxwv ntawm Raman ntawm 1509 cm-1.5%, yog li ntawd, txoj hauv kev no yuav tsum dhau los ua lub hauv paus tseem ceeb rau kev txiav txim siab yog tias cov neeg mob uas muaj tus kab mob coronary artery xav tau PCI, ua kom muaj txiaj ntsig zoo rau kev tshawb pom ntxov ntawm kev xav tias muaj tus kab mob coronary artery.
Muab qhov keeb kwm yav dhau los no, peb lub tuam txhab tau ua tiav cov txiaj ntsig ntawm peb cov kev tshawb fawb yav dhau los los ntawm kev nthuav tawm Platelet Derived Growth Factor Analyzer.Cov cuab yeej no yuav hloov pauv qhov kev nce qib thiab kev siv dav ntawm kev kuaj pom kab mob plawv thaum ntxov.Nws yuav ua rau muaj txiaj ntsig zoo rau kev txhim kho ntawm lub plawv coronary kev noj qab haus huv hauv Suav teb thiab thoob ntiaj teb.
Cov ntawv sau cia
[1] Huinan YJ, Chengxing Shen, Xiaoshu Cai et al.Noninvasive thiab yav tom ntej kev kuaj mob ntawm cov kab mob plawv nrog cov zis siv qhov chaw zoo nkauj Raman spectroscopy [J].Analyst, 2018, 143, 2235–2242.
Parameter nplooj ntawv
| tus qauv naj npawb | SEB-C100 |
| xeem yam khoom | Kev siv ntawm platelet-derived kev loj hlob yam yam ntxwv peaks hauv cov zis |
| Kev sim | automation |
| Lus | Suav |
| Detection Principple | Raman spectroscopy |
| kev sib txuas lus interface | Micro USB Chaw nres nkoj, Network Chaw nres nkoj, WiFi |
| rov ua tau | Coefficient ntawm kev sib txawv ntawm kev xeem ≤ 1.0% |
| degree ntawm qhov raug | Cov txiaj ntsig tau zoo sib xws nrog cov qauv tsim nyog ntawm cov qauv sib xws. |
| ruaj khov | Coefficient ntawm kev sib txawv ≤1.0% rau tib tus qauv hauv 8 teev ntawm lub hwj chim-on |
| Cov txheej txheem kaw | LCD zaub, FlashROM cov ntaub ntawv khaws cia |
| tshawb nrhiav lub sijhawm | Kev kuaj xyuas lub sij hawm rau ib qho qauv yog tsawg dua 120 vib nas this |
| Lub zog ua haujlwm | Lub hwj chim adapter: AC 100V ~ 240V, 50 / 60Hz |
| sab nraud qhov ntev | 700mm (L) * 560mm (W) * 400mm (H) |
| hnyav | Txog 75 kg |
| ib puag ncig ua haujlwm | Ua haujlwm kub: 10 ℃ ~ 30 ℃;txheeb ze av noo: ≤90%;cua siab: 86kPa ~ 106kPa |
| Kev thauj mus los thiab chaw cia khoom | Ua haujlwm kub: -40 ℃ ~ 55 ℃;txheeb ze av noo: ≤95%;cua siab: 86kPa ~ 106kPa |
